Title : p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD.

Pub. Date : 2001 Aug 14

PMID : 11493700






1 Functional Relationships(s)
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1 Rapamycin inhibited mitochondrial-based p70S6K, which prevented phosphorylation of Ser-136 on BAD and blocked cell survival induced by insulin-like growth factor 1 (IGF-1). Sirolimus ribosomal protein S6 kinase B1 Homo sapiens