Title : Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.

Pub. Date : 2001 Aug

PMID : 11479630






1 Functional Relationships(s)
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1 Xeroderma pigmentosum cells deficient in the NER genes XPG, XPA, XPD or XPF were resistant to Et743, and sensitivity was restored by complementation with wild-type genes. Trabectedin ERCC excision repair 4, endonuclease catalytic subunit Homo sapiens