Title : The Acyl-CoA synthetases encoded within FAA1 and FAA4 in Saccharomyces cerevisiae function as components of the fatty acid transport system linking import, activation, and intracellular Utilization.

Pub. Date : 2001 Oct 5

PMID : 11477098






2 Functional Relationships(s)
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1 Faa1p or Faa4p are essential for long-chain fatty acid import, suggesting that one or both of these enzymes are components of the fatty acid transport system, which also includes Fat1p. long-chain fatty acid long-chain fatty acid-CoA ligase FAA1 Saccharomyces cerevisiae S288C
2 By monitoring the intracellular accumulation of the fluorescent long-chain fatty acid analogue 4,4-difluoro-5-methyl-4-bora-3a,4a-diaza-s-indacene-3-dodecanoic acid, long-chain fatty acid transport was shown to be severely restricted in a faa1 Delta faa4 Delta strain. long-chain fatty acid long-chain fatty acid-CoA ligase FAA1 Saccharomyces cerevisiae S288C