Title : Tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy cooperate to induce apoptosis in mesothelioma cell lines.

Pub. Date : 2001 Jul

PMID : 11472983






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 TRAIL plus chemotherapy (doxorubicin, cis-platinum, etoposide, or gemcitabine) acted cooperatively to induce apoptosis in mesothelioma cells (M28, REN, VAMT, and MS-1). Doxorubicin TNF superfamily member 10 Homo sapiens
2 For example, in M28 cells treated for 18 h, apoptosis from TRAIL (100 ng/ml) plus doxorubicin (0.6 microg/ml; 71 +/- 11%) greatly exceeded that from TRAIL alone (21 +/- 8%) or from doxorubicin alone (6 +/- 2%) (means +/- standard deviation; P < 0.03). Doxorubicin TNF superfamily member 10 Homo sapiens