Title : Glutathione S-transferase mu1 null genotype is associated with K-ras gene mutation in lung adenocarcinoma among smokers.

Pub. Date : 2001 Aug

PMID : 11470766






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These findings suggest that the cause of K-ras gene mutation in smokers with lung adenocarcinoma may be in part an accumulation of BP diol epoxide which is not well detoxified in individuals with the GSTM1 null genotype. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide KRAS proto-oncogene, GTPase Homo sapiens