Pub. Date : 2001 Aug
PMID : 11469895
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | cAMP inhibits inducible nitric oxide synthase expression and NF-kappaB-binding activity in cultured rat hepatocytes. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |
| 2 | Adenosine 3",5"-cyclic monophosphate (cAMP) increases iNOS expression and activity in a number of cell types but decreases cytokine-stimulated iNOS expression in hepatocytes. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |
| 3 | Adenosine 3",5"-cyclic monophosphate (cAMP) increases iNOS expression and activity in a number of cell types but decreases cytokine-stimulated iNOS expression in hepatocytes. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |
| 4 | Adenosine 3",5"-cyclic monophosphate (cAMP) increases iNOS expression and activity in a number of cell types but decreases cytokine-stimulated iNOS expression in hepatocytes. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |
| 5 | Adenosine 3",5"-cyclic monophosphate (cAMP) increases iNOS expression and activity in a number of cell types but decreases cytokine-stimulated iNOS expression in hepatocytes. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |
| 6 | CONCLUSION: These data suggest that cAMP is important in hepatocyte iNOS expression and agents that alter cAMP levels may profoundly alter the response of hepatocytes to inflammatory stimuli through effects onthe iNOS promoter region and NF-kappaB. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |
| 7 | CONCLUSION: These data suggest that cAMP is important in hepatocyte iNOS expression and agents that alter cAMP levels may profoundly alter the response of hepatocytes to inflammatory stimuli through effects onthe iNOS promoter region and NF-kappaB. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |
| 8 | CONCLUSION: These data suggest that cAMP is important in hepatocyte iNOS expression and agents that alter cAMP levels may profoundly alter the response of hepatocytes to inflammatory stimuli through effects onthe iNOS promoter region and NF-kappaB. | Cyclic AMP | nitric oxide synthase 2 | Rattus norvegicus |