Title : HIV-protease inhibitors contribute to P-glycoprotein efflux function defect in peripheral blood lymphocytes from HIV-positive patients receiving HAART.

Pub. Date : 2001 Aug 1

PMID : 11468419






1 Functional Relationships(s)
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1 We found that HIV-PIs (i.e., ritonavir, saquinavir, nelfinavir and indinavir) interfere with P-gp function in normal PBLs as demonstrated by the reduced efflux of rhodamine 123 (Rh123). Nelfinavir ATP binding cassette subfamily B member 1 Homo sapiens