Pub. Date : 2001 Aug
PMID : 11457654
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Active efflux of the 5-HT(1A) receptor agonist flesinoxan via P-glycoprotein at the blood-brain barrier. | flesinoxan | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 2 | The role of P-glycoprotein on the efflux of the 5-HT(1A) receptor agonist flesinoxan across the blood-brain barrier in vivo and in vitro was investigated. | flesinoxan | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 3 | In conclusion, both in vivo as well as in vitro results have demonstrated that Pgp is a limiting factor for the transport of the 5-HT(1A) receptor agonist flesinoxan into the CNS. | flesinoxan | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |