Title : Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs.

Pub. Date : 2001 Aug

PMID : 11454927






1 Functional Relationships(s)
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1 In addition, desipramine significantly reduced immobility in the Dbh(-/-) mice following pretreatment with the synthetic NE precursor L-threo-3,4-dihydroxyphenylserine, but not saline. Desipramine dopamine beta hydroxylase Mus musculus