| Protein Name | dopamine beta hydroxylase |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13166 |
| Gene Symbol | Dbh |
| UniProt | Q64237 (DOPO_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
82
Total Number of Articles : 112 |
Description |
dopamine beta hydroxylase |
| Gene Summary |
Predicted to enable copper ion binding activity and dopamine beta-monooxygenase activity. Involved in catecholamine metabolic process; locomotory behavior; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including behavioral response to ethanol; homoiothermy; and learning or memory. Located in secretory granule lumen and secretory granule membrane. Is expressed in several structures, including adrenal gland; alimentary system; and nervous system. Used to study dopamine beta-hydroxylase deficiency. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; dopamine beta-hydroxylase deficiency; hypertension; and migraine with aura. Orthologous to human DBH (dopamine beta-hydroxylase). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |