Title : Inhibition and inactivation of human cytochrome P450 isoforms by phenethyl isothiocyanate.

Pub. Date : 2001 Aug

PMID : 11454729






1 Functional Relationships(s)
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Protein Name
Organism
1 PEITC competitively inhibited phenacetin O-deethylase activity catalyzed by CYP1A2 (K(i) = 4.5 +/- 1.0 microM) and coumarin 7-hydroxylase activity catalyzed by CYP2A6 (K(i) = 18.2 +/- 2.5 microM). phenethyl isothiocyanate cytochrome P450 family 1 subfamily A member 2 Homo sapiens