Title : Chylomicron metabolism by the isolated perfused mouse heart.

Pub. Date : 2001 Aug

PMID : 11440913






5 Functional Relationships(s)
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1 This heparin-releasable LPL pool remained constant over a variety of experimental conditions, including workload and fatty acid concentrations, making the mouse heart a suitable model to study chylomicron catabolism. Fatty Acids lipoprotein lipase Mus musculus
2 Endothelium-bound LPL hydrolyzed radiolabeled (3)H-labeled chylomicrons (0.4 mM TG); the fate of LPL-derived (3)H-labeled fatty acids was split evenly between oxidation (production of (3)H(2)O) and esterification (incorporation into tissue lipids, mainly TG). Fatty Acids lipoprotein lipase Mus musculus
3 Endothelium-bound LPL hydrolyzed radiolabeled (3)H-labeled chylomicrons (0.4 mM TG); the fate of LPL-derived (3)H-labeled fatty acids was split evenly between oxidation (production of (3)H(2)O) and esterification (incorporation into tissue lipids, mainly TG). Fatty Acids lipoprotein lipase Mus musculus
4 These results suggest that fatty acids produced from lipoprotein hydrolysis by the action of LPL and fatty acids from a fatty acid-albumin complex do not enter a common metabolic pool in the heart. Fatty Acids lipoprotein lipase Mus musculus
5 These results suggest that fatty acids produced from lipoprotein hydrolysis by the action of LPL and fatty acids from a fatty acid-albumin complex do not enter a common metabolic pool in the heart. Fatty Acids lipoprotein lipase Mus musculus