Title : Tacrolimus inhibits cytokine production and chemical mediator release following antigen stimulation of passively sensitized human lung tissues.

Pub. Date : 2001 Jun

PMID : 11428741






2 Functional Relationships(s)
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1 OBJECTIVES: We compared the effects of tacrolimus on interleukin (IL)-5 and tumor necrosis factor-alpha (TNF-alpha) production and chemical mediator release from excised human lung tissue with those of steroids. Tacrolimus tumor necrosis factor Homo sapiens
2 Tacrolimus and dexamethasone significantly inhibited TNF-alpha and IL-5 protein production and mRNA expression. Tacrolimus tumor necrosis factor Homo sapiens