Pub. Date : 2001 Jul
PMID : 11423472
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By using inhibitors of the different signaling pathways evoked by insulin-receptor binding, it has been shown that the biosynthesis of PAI-1 is due to phosphatidylinositol (PI) 3-kinase activation, followed by protein kinase C and ultimately by mitogen-activated protein (MAP) kinase activation and extracellular signal-regulated kinase 2 phosphorylation. | Phosphatidylinositols | insulin receptor | Homo sapiens |