Pub. Date : 2001 Jun 29
PMID : 11419942
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The activities of three Rab-specific factors with GDP/GTP exchange activity, Vps9p, Rabex-5 and DSS4, with their cognate GTPases, Ypt51p, Rab5 and Ypt1p, have been analysed quantitatively. | Guanosine Triphosphate | RAB1A, member RAS oncogene family | Homo sapiens |
| 2 | An additional, and based on present knowledge, unique, feature of the Ypt1p.DSS4 complex, is that the association of GTP (or GDP) is more than 10(3)-fold slower than to Ypt1p, thus leading to a long life-time of the binary complex between the two proteins, even at the high nucleotide concentrations that prevail in the cell. | Guanosine Triphosphate | RAB1A, member RAS oncogene family | Homo sapiens |