Title : Diverse roles of conserved asparagine-linked glycan sites on tyrosinase family glycoproteins.

Pub. Date : 2001 Jul 1

PMID : 11412044






2 Functional Relationships(s)
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1 The role of conserved N-glycan sites in sorting, stability, and activity of tyrosinase family proteins was investigated using two family members from two different species, mouse gp75/tyrosinase-related protein (TRP)-1/Tyrp1 and human tyrosinase. n-glycan tyrosinase Homo sapiens
2 Our results show that selected conserved N-glycan sites on tyrosinase family members are crucial for stability in the secretory pathway and endocytic compartment and for enzymatic activity. n-glycan tyrosinase Homo sapiens