Pub. Date : 2001 Jul
PMID : 11408533
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The nAChR subtype mediating nicotine-induced dilation in isolated porcine basilar arterial rings denuded of endothelium was therefore examined pharmacologically and immunohistochemically. | Nicotine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 2 | Results from using an in vitro tissue bath technique indicated that relaxation induced by nicotine (100 microM) was blocked by preferential alpha7-nAChR antagonists (methyllycaconitine and alpha-bungarotoxin) and nonspecific nAChR antagonist (mecamylamine) in a concentration-dependent manner, but was not affected by dihydro-beta-erythroidine (a preferential alpha4-nAChR antagonist). | Nicotine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 3 | Results from using an in vitro tissue bath technique indicated that relaxation induced by nicotine (100 microM) was blocked by preferential alpha7-nAChR antagonists (methyllycaconitine and alpha-bungarotoxin) and nonspecific nAChR antagonist (mecamylamine) in a concentration-dependent manner, but was not affected by dihydro-beta-erythroidine (a preferential alpha4-nAChR antagonist). | Nicotine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 4 | Results from using an in vitro tissue bath technique indicated that relaxation induced by nicotine (100 microM) was blocked by preferential alpha7-nAChR antagonists (methyllycaconitine and alpha-bungarotoxin) and nonspecific nAChR antagonist (mecamylamine) in a concentration-dependent manner, but was not affected by dihydro-beta-erythroidine (a preferential alpha4-nAChR antagonist). | Nicotine | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |