Title : Melatonin activates PKC-alpha but not PKC-epsilon in N1E-115 cells.

Pub. Date : 2001 Aug

PMID : 11408087






8 Functional Relationships(s)
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1 Melatonin activates PKC-alpha but not PKC-epsilon in N1E-115 cells. Melatonin protein kinase C, alpha Mus musculus
2 In this work, we further characterize the activation of PKC by melatonin in neuroblastoma N1E-115 cells. Melatonin protein kinase C, alpha Mus musculus
3 The results showed that both melatonin and the PKC agonist phorbol-12-myristate-13-acetate increased PKC activity in isolated IFs. Melatonin protein kinase C, alpha Mus musculus
4 In intact N1E-115 cells, melatonin elicited PKC-alpha translocation and no changes were detected in PKC-epsilon. Melatonin protein kinase C, alpha Mus musculus
5 The results showed that melatonin selectively activates the Ca(2+)-dependent alpha isoform of PKC and suggest that PKC-alpha activation by melatonin underlies IF rearrangements and participates in neurite formation in N1E-115 cells. Melatonin protein kinase C, alpha Mus musculus
6 The results showed that melatonin selectively activates the Ca(2+)-dependent alpha isoform of PKC and suggest that PKC-alpha activation by melatonin underlies IF rearrangements and participates in neurite formation in N1E-115 cells. Melatonin protein kinase C, alpha Mus musculus
7 The results showed that melatonin selectively activates the Ca(2+)-dependent alpha isoform of PKC and suggest that PKC-alpha activation by melatonin underlies IF rearrangements and participates in neurite formation in N1E-115 cells. Melatonin protein kinase C, alpha Mus musculus
8 The results showed that melatonin selectively activates the Ca(2+)-dependent alpha isoform of PKC and suggest that PKC-alpha activation by melatonin underlies IF rearrangements and participates in neurite formation in N1E-115 cells. Melatonin protein kinase C, alpha Mus musculus