Title : Inhibitory effect of steroidal alkaloids on drug transport and multidrug resistance in human cancer cells.

Pub. Date : 2001 Mar-Apr

PMID : 11396162






1 Functional Relationships(s)
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1 It is concluded that steroidal alkaloids of plant origin act as inhibitors of P-gp-mediated drug transport and multidrug resistance and therefore may serve as chemosensitizers in combination chemotherapy with conventional cytotoxic drugs for treating multidrug resistant cancer. Alkaloids ATP binding cassette subfamily B member 1 Homo sapiens