Pub. Date : 2001 Jun
PMID : 11389120
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We investigated the effects of azithromycin and clarithromycin, two antibiotics that possess a broad spectrum of antimicrobial activity (including antimycobacterial activity), on interleukin-8 (IL-8) release from human whole blood leucocytes and lung macrophages. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
2 | We investigated the effects of azithromycin and clarithromycin, two antibiotics that possess a broad spectrum of antimicrobial activity (including antimycobacterial activity), on interleukin-8 (IL-8) release from human whole blood leucocytes and lung macrophages. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
3 | Incubation of alveolar macrophages with different concentrations of azithromycin or clarithromycin modified IL-8 production: it increased at a drug concentration of 4 mg/L and decreased at concentration of 400 mg/L. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
4 | Our findings suggest that azithromycin and clarithromycin may alter IL-8 production, thus enhancing the clinical effectiveness of these antibiotics. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |