PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11389120-1 2001 We investigated the effects of azithromycin and clarithromycin, two antibiotics that possess a broad spectrum of antimicrobial activity (including antimycobacterial activity), on interleukin-8 (IL-8) release from human whole blood leucocytes and lung macrophages. Azithromycin 31-43 C-X-C motif chemokine ligand 8 Homo sapiens 179-192 11389120-1 2001 We investigated the effects of azithromycin and clarithromycin, two antibiotics that possess a broad spectrum of antimicrobial activity (including antimycobacterial activity), on interleukin-8 (IL-8) release from human whole blood leucocytes and lung macrophages. Azithromycin 31-43 C-X-C motif chemokine ligand 8 Homo sapiens 194-198 11389120-3 2001 Incubation of alveolar macrophages with different concentrations of azithromycin or clarithromycin modified IL-8 production: it increased at a drug concentration of 4 mg/L and decreased at concentration of 400 mg/L. Azithromycin 68-80 C-X-C motif chemokine ligand 8 Homo sapiens 108-112 11389120-4 2001 Our findings suggest that azithromycin and clarithromycin may alter IL-8 production, thus enhancing the clinical effectiveness of these antibiotics. Azithromycin 26-38 C-X-C motif chemokine ligand 8 Homo sapiens 68-72