Title : Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects?

Pub. Date : 2001 Jun

PMID : 11386852






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Theoretically, mutated SHMT could lead to elevated Hcy levels and to an altered distribution of the different folate derivatives and might therefore become a risk factor for NTD. Folic Acid serine hydroxymethyltransferase 1 Homo sapiens
2 Still, the influence of the 1420 C>T polymorphism of the cSHMT gene on the folate-related risk of NTD needs further investigation. Folic Acid serine hydroxymethyltransferase 1 Homo sapiens