PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11378569-2 2001 We have identified activating mutations of c-kit at codon 816 (Asp(816) ) from a revertant of the cytokine-dependent acute myeloid leukemia (AML) cell line, MO7e (D816H), and de novo childhood AML (D816N). Aspartic Acid 63-66 KIT proto-oncogene, receptor tyrosine kinase Homo sapiens 43-48 11378569-5 2001 These results suggest a potentially important role of Asp(816) mutations of c-kit in both malignant cell proliferation and resistance to therapy. Aspartic Acid 54-57 KIT proto-oncogene, receptor tyrosine kinase Homo sapiens 76-81