Title : Peroxisome proliferator-activated receptors (PPARs): nuclear receptors with functions in the vascular wall.

Pub. Date : 2001

PMID : 11374025






4 Functional Relationships(s)
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1 PPAR alpha is highly expressed in liver, muscle, kidney and heart, where it stimulates the beta-oxidative degradation of fatty acids. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens
2 Furthermore, fatty acid-derivatives and eicosanoids are natural PPAR ligands: PPAR alpha is activated by leukotriene B4, whereas prostaglandin J2 is a PPAR gamma ligand, as well as some components of oxidized LDL, such as 9- and 13-HODE. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens
3 Furthermore, fatty acid-derivatives and eicosanoids are natural PPAR ligands: PPAR alpha is activated by leukotriene B4, whereas prostaglandin J2 is a PPAR gamma ligand, as well as some components of oxidized LDL, such as 9- and 13-HODE. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens
4 Furthermore, fatty acid-derivatives and eicosanoids are natural PPAR ligands: PPAR alpha is activated by leukotriene B4, whereas prostaglandin J2 is a PPAR gamma ligand, as well as some components of oxidized LDL, such as 9- and 13-HODE. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens