Title : Mapping the determinants of the CCR5 amino-terminal sulfopeptide interaction with soluble human immunodeficiency virus type 1 gp120-CD4 complexes.

Pub. Date : 2001 Jun

PMID : 11356961






2 Functional Relationships(s)
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Protein Name
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1 Sulfotyrosine and other negatively charged residues in the CCR5 amino-terminal domain (Nt) are crucial for gp120 binding and viral entry. tyrosine O-sulfate C-C motif chemokine receptor 5 Homo sapiens
2 We previously showed that a soluble gp120-CD4 complex specifically binds to a peptide corresponding to CCR5 Nt residues 2 to 18, with sulfotyrosines in positions 10 and 14. tyrosine O-sulfate C-C motif chemokine receptor 5 Homo sapiens