Title : Cell line dependent involvement of ceramide in ultraviolet light-induced apoptosis.

Pub. Date : 2001 Mar

PMID : 11354249






1 Functional Relationships(s)
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1 Inhibition of ceramide production by desipramine (25-50 microM) reduced UV-induced JNK activation in both 293 and Jurkat cells; and protects 293 cells from UV-induced apoptosis. Desipramine mitogen-activated protein kinase 8 Homo sapiens