Title : Impairment of CD8+ T suppressor cell function in patients with active systemic lupus erythematosus.

Pub. Date : 2001 May 15

PMID : 11342672






1 Functional Relationships(s)
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1 Two cytokines, IFN-gamma and IL-6, were found to be responsible for the function of CD8(+) TS: In fact, counteraction of CD8(+) Ts suppression activity was obtained by blocking IFN-gamma with a specific Ab or by inhibiting CD8(+) Ts-mediated IL-6 secretion by an antisense oligonucleotide. Oligonucleotides interleukin 6 Homo sapiens