Title : Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase Cdelta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation.

Pub. Date : 2001 Jul 20

PMID : 11335711






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Activation of signal transducer and activator of transcription 3 (STAT3) by interleukin-6 (IL-6) involves phosphorylation of Tyr-705 and Ser-727, both of which are critical for STAT3 transactivation. Tyrosine interleukin 6 Homo sapiens
2 Activation of signal transducer and activator of transcription 3 (STAT3) by interleukin-6 (IL-6) involves phosphorylation of Tyr-705 and Ser-727, both of which are critical for STAT3 transactivation. Tyrosine interleukin 6 Homo sapiens