Title : Delavirdine: clinical pharmacokinetics and drug interactions.

Pub. Date : 2001

PMID : 11327199






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Delavirdine undergoes extensive metabolism by cytochrome P450 (CYP) with little urinary excretion of unchanged drug. Delavirdine cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Delavirdine undergoes extensive metabolism by cytochrome P450 (CYP) with little urinary excretion of unchanged drug. Delavirdine cytochrome P450 family 4 subfamily F member 3 Homo sapiens
3 Concomitant use of CYP inducers, such as rifampicin (rifampin), rifabutin, phenytoin, phenobarbital or carbamazepine, should be avoided since delavirdine plasma concentrations are significantly lowered. Delavirdine cytochrome P450 family 4 subfamily F member 3 Homo sapiens