Pub. Date : 2001 May
PMID : 11302935
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7. | Epirubicin | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 2 | Only UGT2B7 converted epirubicin to its glucuronide. | Epirubicin | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 3 | Catalytic efficiency (V(max)/K(m)) of epirubicin glucuronidation was 1.4 microl/min/mg, a value higher than that observed for morphine, a substrate of UGT2B7. | Epirubicin | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 4 | UGT2B7 is the major human UGT catalyzing epirubicin glucuronidation, and UGT2B7 is the candidate gene for this phenotype. | Epirubicin | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 5 | UGT2B7 is the major human UGT catalyzing epirubicin glucuronidation, and UGT2B7 is the candidate gene for this phenotype. | Epirubicin | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |