Title : Regulation of TNFalpha and interleukin-10 production by prostaglandins I(2) and E(2): studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists.

Pub. Date : 2001 May 1

PMID : 11301049






2 Functional Relationships(s)
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1 To know which receptors of prostaglandins are involved in the regulation of TNFalpha and interleukin 10 (IL-10) production, we examined the production of these cytokines in murine peritoneal macrophages stimulated with zymosan. Prostaglandins tumor necrosis factor Mus musculus
2 These functional effects of prostaglandins well accorded with the mRNA expression of TNFalpha and IL-10 when such expression was examined by the RT-PCR method. Prostaglandins tumor necrosis factor Mus musculus