Title : Stress-induced hyperthermia in the 5-HT(1A) receptor knockout mouse is normal.

Pub. Date : 2001 Apr 1

PMID : 11297713






2 Functional Relationships(s)
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1 Moreover, on pharmacologic challenges with the 5-HT(1A) receptor agonist flesinoxan we expected an absence of the functional response in knockout mice relative to wild type mice. flesinoxan 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
2 METHODS: Effects of the 5-HT(1A) receptor agonist flesinoxan, alone or in combination with the 5-HT(1A) receptor antagonist WAY-100635, and the gamma-aminobutyric acid A (GABA(A))-benzodiazepine receptor agonist diazepam were studied in the SIH paradigm in male 129/Sv 5-HT(1A) receptor knockout and wild type mice. flesinoxan 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus