Title : Genetic polymorphisms in DNA repair genes and risk of lung cancer.

Pub. Date : 2001 Apr

PMID : 11285194






5 Functional Relationships(s)
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1 The XPD codon 312 Asp/Asp genotype was found to have almost twice the risk of lung cancer when the Asp/Asn + Asn/Asn combined genotype served as reference [odds ratio (OR) 1.86, 95% confidence interval (CI), 1.02-3.40]. Aspartic Acid ERCC excision repair 2, TFIIH core complex helicase subunit Homo sapiens
2 The XPD codon 312 Asp/Asp genotype was found to have almost twice the risk of lung cancer when the Asp/Asn + Asn/Asn combined genotype served as reference [odds ratio (OR) 1.86, 95% confidence interval (CI), 1.02-3.40]. Aspartic Acid ERCC excision repair 2, TFIIH core complex helicase subunit Homo sapiens
3 The XPD codon 312 Asp/Asp genotype was found to have almost twice the risk of lung cancer when the Asp/Asn + Asn/Asn combined genotype served as reference [odds ratio (OR) 1.86, 95% confidence interval (CI), 1.02-3.40]. Aspartic Acid ERCC excision repair 2, TFIIH core complex helicase subunit Homo sapiens
4 In light cigarette smokers (less than the median of 34.5 pack-years), the XPD codon 312 Asp/Asp genotype was more frequent among cases than in controls and was associated with an increased risk of NSCLC. Aspartic Acid ERCC excision repair 2, TFIIH core complex helicase subunit Homo sapiens
5 In light cigarette smokers (less than the median of 34.5 pack-years), the XPD codon 312 Asp/Asp genotype was more frequent among cases than in controls and was associated with an increased risk of NSCLC. Aspartic Acid ERCC excision repair 2, TFIIH core complex helicase subunit Homo sapiens