Title : Rho and Rac but not Cdc42 regulate endothelial cell permeability.

Pub. Date : 2001 Apr

PMID : 11257000






1 Functional Relationships(s)
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Protein Name
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1 Dominant-negative RhoA and a Rho kinase inhibitor, Y-27632, not only inhibit stress fibre assembly and contractility but also prevent thrombin- and histamine-induced disassembly of adherens and tight junctions in endothelial cells, providing an explanation for their effects on permeability. Y 27632 coagulation factor II, thrombin Homo sapiens