Title : The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.

Pub. Date : 2001 Mar 13

PMID : 11248085






4 Functional Relationships(s)
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1 The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16alpha-carbonitrile (PCN), which induce cytochrome P450 3A (CYP3A) expression and protect the body from harmful chemicals. Pregnenolone Carbonitrile cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16alpha-carbonitrile (PCN), which induce cytochrome P450 3A (CYP3A) expression and protect the body from harmful chemicals. Pregnenolone Carbonitrile cytochrome P450 family 3 subfamily A member 4 Homo sapiens
3 The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16alpha-carbonitrile (PCN), which induce cytochrome P450 3A (CYP3A) expression and protect the body from harmful chemicals. Pregnenolone Carbonitrile cytochrome P450 family 3 subfamily A member 4 Homo sapiens
4 The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16alpha-carbonitrile (PCN), which induce cytochrome P450 3A (CYP3A) expression and protect the body from harmful chemicals. Pregnenolone Carbonitrile cytochrome P450 family 3 subfamily A member 4 Homo sapiens