Title : GRK3 mediates desensitization of CRF1 receptors: a potential mechanism regulating stress adaptation.

Pub. Date : 2001 Apr

PMID : 11247813






1 Functional Relationships(s)
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1 Furthermore, Y-79 cell uptake of a GRK3 antisense oligonucleotide (ODN), but not of a random or mismatched ODN, reduced GRK3 mRNA expression by approximately 50% without altering GRK2 mRNA expression and inhibited homologous desensitization of CRF1 receptors by approximately 55%. odn corticotropin releasing hormone receptor 1 Homo sapiens