Protein Name corticotropin releasing hormone receptor 1
Organism Homo sapiens
Gene ID 1394
Gene Symbol

CRHR1

UniProt P34998 (CRFR1_HUMAN), B3TIK8 (B3TIK8_HUMAN), K9J956 (K9J956_HUMAN), A0A024R9X9 (A0A024R9X9_HUMAN), B3SXS2 (B3SXS2_HUMAN), G3CIS4 (G3CIS4_HUMAN)
Relationships Total Number of functionally related compound(s) : 202
Total Number of Articles : 235
Description

corticotropin releasing hormone receptor 1

Gene Summary

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Aug 2016]

synonyms
  • corticotropin-releasing factor receptor 1
  • corticotropin-releasing factor type 1 receptor
  • seven transmembrane helix receptor
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Properties