Title : [Inhibition effect of Amaryllidaceae alkaloids, lycorine and lycoricidinol on macrophage TNF-alpha production].

Pub. Date : 2001 Feb

PMID : 11218731

2 Functional Relationships(s)
Compound Name
Protein Name
1 To explore further the mechanism of the suppression for inflammation, we studied the effect of the alkaloids on macrophage tumor necrosis factor (TNF-alpha) production in vitro, since TNF-alpha is recognized as a pivotal cytokine to regulate inflammation. Alkaloids tumor necrosis factor Rattus norvegicus
2 From these results, it was concluded that these alkaloids exert inhibitory effects not only on neutrophil apoptosis-inducing protein, calprotectin, but also on macrophage TNF-alpha production. Alkaloids tumor necrosis factor Rattus norvegicus