Title : Neurotrophic effects of central nicotinic receptor activation.

Pub. Date : 2000

PMID : 11205143






1 Functional Relationships(s)
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1 This neuroprotective/trophic role of nAChR activation has been mainly mediated by alpha7 and alpha4beta2 nAChR subtypes, as evidenced using selective nAChR antagonists, and by potent nAChR agonists recently found displaying efficacy and/or larger selective affinities than (-)-nicotine for neuronal nAChR subtypes. Nicotine cholinergic receptor nicotinic alpha 4 subunit Homo sapiens