Pub. Date : 2000
PMID : 11200365
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | AIMS: The aim of this work was to examine whether the administration of cyclosporin-A (Cs-A) to STZ-induced diabetic rats inhibits the synthesis of IL-1beta and the expression of the inducible proteins, iNOS and cyclo-oxygenase-2 (COX-2) in retinal cells, and whether the activity of these proteins contribute to BRB breakdown. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |
2 | AIMS: The aim of this work was to examine whether the administration of cyclosporin-A (Cs-A) to STZ-induced diabetic rats inhibits the synthesis of IL-1beta and the expression of the inducible proteins, iNOS and cyclo-oxygenase-2 (COX-2) in retinal cells, and whether the activity of these proteins contribute to BRB breakdown. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |
3 | The treatment of diabetic rats with Cs-A also significantly inhibited the expression of the inducible proteins, iNOS and COX-2. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |