Title : Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.

Pub. Date : 2001 Jan 1

PMID : 11196191






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 On IL-6 stimulation, SHP-2 and Gab1 were recruited to the gp130 subunit of the IL-6 receptor and tyrosine phosphorylated, allowing downstream signaling to the MAPK and PI3K pathways. Tyrosine interleukin 6 Homo sapiens
2 On IL-6 stimulation, SHP-2 and Gab1 were recruited to the gp130 subunit of the IL-6 receptor and tyrosine phosphorylated, allowing downstream signaling to the MAPK and PI3K pathways. Tyrosine interleukin 6 Homo sapiens