Title : Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo.

Pub. Date : 2001 Mar

PMID : 11179472






1 Functional Relationships(s)
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1 Growth factors interact with their cell surface receptors and activate the enzyme PI 3-kinase (PI 3-K) resulting in the formation of 3-phosphorylated phosphatidylinositols, which in turn activate the serine/threonine kinase AKT/PKB. Phosphatidylinositols phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Homo sapiens