Title : A novel approach to thymidylate synthase as a target for cancer chemotherapy.

Pub. Date : 2001 Mar

PMID : 11179438






1 Functional Relationships(s)
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1 We show herein that tumor cells expressing elevated levels of TS are preferentially sensitive to NB1011, a phosphoramidate derivative of (E)-5-(2-bromovinyl)-2"-deoxyuridine. phosphoramidic acid thymidylate synthetase Homo sapiens