Title : Urethane anaesthesia could partly mask antinociceptive effects of non-steroidal anti-inflammatory drugs: a spinal c-Fos protein study.

Pub. Date : 2001 Feb 9

PMID : 11164833






3 Functional Relationships(s)
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1 Urethane anaesthesia could partly mask antinociceptive effects of non-steroidal anti-inflammatory drugs: a spinal c-Fos protein study. Urethane Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 Urethane anaesthesia strongly reduced the peripheral edema (31+/-5 and 96+/-8% reduction of carrageenan-enhanced paw and ankle diameters, respectively; P<0.001 for both) and the spinal c-Fos protein expression (71+/-4% reduction of the number of c-Fos protein-labeled nuclei; P<0.001), 3 h after intraplantar injection of carrageenan in rats. Urethane Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 Urethane anaesthesia strongly reduced the peripheral edema (31+/-5 and 96+/-8% reduction of carrageenan-enhanced paw and ankle diameters, respectively; P<0.001 for both) and the spinal c-Fos protein expression (71+/-4% reduction of the number of c-Fos protein-labeled nuclei; P<0.001), 3 h after intraplantar injection of carrageenan in rats. Urethane Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus