Title : Kinetic profiling of P-glycoprotein-mediated drug efflux in rat and human intestinal epithelia.

Pub. Date : 2001 Feb

PMID : 11160647






1 Functional Relationships(s)
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1 Inhibitor studies showed that digoxin and vinblastine efflux in intestinal tissues was mediated by P-glycoprotein, although a minor component could be attributed to multidrug resistance-related protein (MRP)-like transporters in Caco-2. Vinblastine ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus