Title : The NO donor molsidomine reduces endothelin-1 gene expression in chronic hypoxic rat lungs.

Pub. Date : 2001 Feb

PMID : 11159004






1 Functional Relationships(s)
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1 Two and four weeks of hypoxia (10% O2) significantly increased right ventricular systolic pressure, the medial cross-sectional vascular wall area of the pulmonary arteries, and pulmonary ET-1 mRNA expression (2-fold and 3.2-fold, respectively). Oxygen endothelin 1 Rattus norvegicus