Title : Regulation of Bcl2 phosphorylation and potential significance for leukemic cell chemoresistance.

Pub. Date : 2001

PMID : 11158204






1 Functional Relationships(s)
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1 However, we have recently found that high concentrations of staurosporine up to 1 microM: can only partially inhibit IL-3-stimulated Bcl2 phosphorylation but completely block PKCalpha-mediated Bcl2 phosphorylation in vitro, indicating the existence of a non-PKC, staurosporine-resistant Bcl2 kinase (SRK). Staurosporine interleukin 3 Homo sapiens