Pub. Date : 2001 Feb
PMID : 11158071
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Increased PAI-1 and tPA antigen levels are reduced with metformin therapy in HIV-infected patients with fat redistribution and insulin resistance. | Metformin | serpin family E member 1 | Homo sapiens |
| 2 | Furthermore, we investigated the effect of treatment with metformin on PAI-1 and tPA antigen levels in patients with HIV-associated fat redistribution. | Metformin | serpin family E member 1 | Homo sapiens |
| 3 | Similarly, metformin resulted in improvement in PAI-1 levels (-8.7 +/- 2.3 vs +1.7 +/- 2.9 microg/L, P = 0.03). | Metformin | serpin family E member 1 | Homo sapiens |
| 4 | Metformin reduces PAI-1 and tPA antigen concentrations in these patients and may ultimately improve associated CVD risk. | Metformin | serpin family E member 1 | Homo sapiens |