Title : Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation.

Pub. Date : 2001 Jan 15

PMID : 11146440






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The dissociation constant of galectin-1 to 90K was on the order of 10(-7) M. Galectin-1 also induced aggregation of a human melanoma cell line, A375, in a carbohydrate-dependent manner, and this appeared to be mediated, at least in part, by 90K expressed on A375 cells, since it was inhibitable by a specific anti-90K monoclonal antibody. Carbohydrates galectin 3 binding protein Homo sapiens