Protein Name galectin 3 binding protein
Organism Homo sapiens
Gene ID 3959
Gene Symbol

LGALS3BP

UniProt Q08380 (LG3BP_HUMAN), A0A0S2Z3Y1 (A0A0S2Z3Y1_HUMAN)
Relationships Total Number of functionally related compound(s) : 99
Total Number of Articles : 102
Description

galectin 3 binding protein

Gene Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

synonyms
  • galectin-3-binding protein
  • L3 antigen
  • MAC2BP
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Properties